Flaugnatti N, Rapisarda C, Rey M, Beauvois SG, Nguyen VA, Canaan S, Durand E, Chamot-Rooke J, Cascales E, Fronzes R, Journet L.
Structural basis for loading and inhibition of a bacterial T6SS phospholipase effector by the VgrG spike.
EMBO J. 2020 Jun 2;39(11):e104129. doi: 10.15252/embj.2019104129. Epub 2020 Apr 30. PMID: 32350888; PMCID: PMC7265238.

Pony P, Rapisarda C, Terradot L, Marza E, Fronzes R.
Filamentation of the bacterial bi-functional alcohol/aldehyde dehydrogenase AdhE is essential for substrate channeling and enzymatic regulation.
Nat Commun. 2020 Mar 18;11(1):1426. doi: 10.1038/s41467-020-15214-y. PMID: 32188856; PMCID: PMC7080775.

Kumar A, Planchais C, Fronzes R, Mouquet H, Reyes N.
Binding mechanisms of therapeutic antibodies to human CD20.
Science. 2020 Aug 14;369(6505):793-799.
doi: 10.1126/science.abb8008. PMID: 32792392.

Rapisarda C, Cherrak Y, Kooger R, Schmidt V, Pellarin R, Logger L, Cascales E, Pilhofer M, Durand E, Fronzes R.
In situ and high-resolution cryo-EM structure of a bacterial type VI secretion system membrane complex.
EMBO J. 2019 May 15;38(10):e100886. doi: 10.15252/embj.2018100886. Epub 2019 Mar 15.

Perry TN, Souabni H, Rapisarda C, Fronzes R, Giusti F, Popot JL, Zoonens M, Gubellini F.
BAmSA: Visualising transmembrane regions in protein complexes using biotinylated amphipols and electron microscopy.
Biochim Biophys Acta Biomembr. 2019 Feb 1;1861(2):466-477. doi:10.1016/j.bbamem.2018.11.004.

Cherrak Y, Rapisarda C, Pellarin R, Bouvier G, Bardiaux B, Allain F, Malosse C, Rey M, Chamot-Rooke J, Cascales E, Fronzes R, Durand E.
Biogenesis and structure of a type VI secretion baseplate.
Nat Microbiol. 2018 Dec;3(12):1404-1416. doi: 10.1038/s41564-018-0260-1. Epub 2018 Oct 15. PMID: 30323254.

Rapisarda C, Tassinari M, Gubellini F, Fronzes R.
Using Cryo-EM to Investigate Bacterial Secretion Systems.
Annu Rev Microbiol. 2018 Sep 8;72:231-254. doi: 10.1146/annurev-micro-090817-062702. Epub 2018 Jul 13. PMID: 30004822.

Krasteva PV, Bernal-Bayard J, Travier L, Martin FA, Kaminski PA, Karimova G, Fronzes R, Ghigo JM.
Insights into the structure and assembly of a bacterial cellulose secretion system.
Nat Commun. 2017 Dec 12;8(1):2065. doi: 10.1038/s41467-017-01523-2. PubMed PMID: 29234007; PubMed Central PMCID: PMC5727187

Koelblen T, Bergé C, Cherrier MV, Brillet K, Jimenez-Soto L, Ballut L, Takagi J, Montserret R, Rousselle P, Fischer W, Haas R, Fronzes R, Terradot L.
Molecular dissection of protein-protein interactions between integrin α5β1 and the Helicobacter pylori Cag type IV secretion system.
FEBS J. 2017 Dec;284(23):4143-4157. doi: 10.1111/febs.14299. Epub 2017 Nov 12. PubMed PMID: 29055076.

Diallo A, Foster HR, Gromek KA, Perry TN, Dujeancourt A, Krasteva PV, Gubellini F, Falbel TG, Burton BM, Fronzes R.
Bacterial transformation: ComFA is a DNA-dependent ATPase that forms complexes with ComFC and DprA.
Mol Microbiol. 2017 Sep;105(5):741-754. doi: 10.1111/mmi.13732. Epub 2017 Jul 28. PubMed PMID: 28618091.

Marie L, Rapisarda C, Morales V, Bergé M, Perry T, Soulet AL, Gruget C, Remaut H, Fronzes R, Polard P.
Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension.
Nat Commun. 2017 May 31;8:15638. doi: 10.1038/ncomms15638. PubMed PMID: 28561029; PubMed Central PMCID: PMC5512693.

Gubellini F, Fronzes R.
Labeling of Membrane Complexes for Electron Microscopy.
Methods Mol Biol. 2017;1635:125-138. doi: 10.1007/978-1-4939-7151-0_7. PubMed PMID: 28755367.

Wojtowicz H, Prochnicka-Chalufour A, de Amorim GC, Roudenko O, Simenel C, Malki I, Pehau-Arnaudet G, Gubellini F, Koutsioubas A, Pérez J, Delepelaire P, Delepierre M, Fronzes R, Izadi-Pruneyre N.
Structural basis of the signalling through a bacterial membrane receptor HasR deciphered by an integrative approach.
Biochem J. 2016 Jul 15;473(14):2239-48. doi: 10.1042/BCJ20160131. Epub 2016 May 13. PubMed PMID: 27208170; PubMed Central PMCID: PMC4941744.

Zoued A, Durand E, Brunet YR, Spinelli S, Douzi B, Guzzo M, Flaugnatti N, Legrand P, Journet L, Fronzes R, Mignot T, Cambillau C, Cascales E.
Priming and polymerization of a bacterial contractile tail structure.
Nature. 2016 Mar 3;531(7592):59-63. doi: 10.1038/nature17182. Epub 2016 Feb 24. PubMed PMID: 26909579.

Durand E, Nguyen VS, Zoued A, Logger L, Péhau-Arnaudet G, Aschtgen MS, Spinelli S, Desmyter A, Bardiaux B, Dujeancourt A, Roussel A, Cambillau C, Cascales E, Fronzes R.
Biogenesis and structure of a type VI secretion membrane core complex.
Nature. 2015 Jul 30;523(7562):555-60. doi: 10.1038/nature14667. Epub 2015 Jul 22. PubMed PMID: 26200339.

Kaplan M, Cukkemane A, van Zundert GC, Narasimhan S, Daniëls M, Mance D, Waksman G, Bonvin AM, Fronzes R, Folkers GE, Baldus M.
Probing a cell-embedded megadalton protein complex by DNP-supported solid-state NMR.
Nat Methods. 2015 Jul;12(7):649-52. doi: 10.1038/nmeth.3406. Epub 2015 May 18. PubMed PMID: 25984698.

Laurenceau R, Krasteva PV, Diallo A, Ouarti S, Duchateau M, Malosse C, Chamot-Rooke J, Fronzes R.
Conserved Streptococcus pneumoniae spirosomes suggest a single type of transformation pilus in competence.
PLoS Pathog. 2015 Apr 15;11(4):e1004835. doi: 10.1371/journal.ppat.1004835. eCollection 2015 Apr. PubMed PMID: 25876066; PubMed Central PMCID: PMC4398557.

Goyal P, Krasteva PV, Van Gerven N, Gubellini F, Van den Broeck I, Troupiotis-Tsaïlaki A, Jonckheere W, Péhau-Arnaudet G, Pinkner JS, Chapman MR, Hultgren SJ, Howorka S, Fronzes R, Remaut H.
Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG.
Nature. 2014 Dec 11;516(7530):250-3. doi: 10.1038/nature13768. Epub 2014 Sep 14. PubMed PMID: 25219853; PubMed Central PMCID: PMC4268158.

Low HH, Gubellini F, Rivera-Calzada A, Braun N, Connery S, Dujeancourt A, Lu F, Redzej A, Fronzes R, Orlova EV, Waksman G.
Structure of a type IV secretion system.
Nature. 2014 Apr 24;508(7497):550-553. doi: 10.1038/nature13081. Epub 2014 Mar 9. PubMed PMID: 24670658; PubMed Central PMCID: PMC3998870.

Laurenceau R, Péhau-Arnaudet G, Baconnais S, Gault J, Malosse C, Dujeancourt A, Campo N, Chamot-Rooke J, Le Cam E, Claverys JP, Fronzes R.
A type IV pilus mediates DNA binding during natural transformation in Streptococcus pneumoniae.
PLoS Pathog. 2013;9(6):e1003473. doi: 10.1371/journal.ppat.1003473. Epub 2013 Jun 27. PubMed PMID: 23825953; PubMed Central PMCID: PMC3694846.

Rivera-Calzada A, Fronzes R, Savva CG, Chandran V, Lian PW, Laeremans T, Pardon E, Steyaert J, Remaut H, Waksman G, Orlova EV.
Structure of a bacterial type IV secretion core complex at subnanometre resolution.
EMBO J. 2013 Apr 17;32(8):1195-204. doi: 10.1038/emboj.2013.58. Epub 2013 Mar 19. PubMed PMID: 23511972;PubMed Central PMCID: PMC3630358.

Daviter T, Fronzes R.
Protein sample characterization.
Methods Mol Biol. 2013;1008:35-62. doi: 10.1007/978-1-62703-398-5_2. PubMed PMID: 23729248

Baranova E, Fronzes R, Garcia-Pino A, Van Gerven N, Papapostolou D, Péhau-Arnaudet G, Pardon E, Steyaert J, Howorka S, Remaut H.
SbsB structure and lattice reconstruction unveil Ca2+ triggered S-layer assembly.
Nature. 2012 Jul 5;487(7405):119-22. doi: 10.1038/nature11155. PubMed PMID: 22722836.

Waksman G, Fronzes R.
Molecular architecture of bacterial type IV secretion systems.
Trends Biochem Sci. 2010 Dec;35(12):691-8. doi: 10.1016/j.tibs.2010.06.002. Epub 2010 Jul 10. Review. PubMed PMID: 20621482.

Rego AT, Fronzes R, Waksman G.
SnapShot: Bacterial appendages II.
Cell. 2010 Jan 22;140(2):294-294.e1. doi: 10.1016/j.cell.2010.01.006. PubMed PMID: 20141842.

Rego AT, Fronzes R, Waksman G.
SnapShot: Bacterial Appendages I.
Cell. 2010 Jan 8;140(1):162-162.e1. doi: 10.1016/j.cell.2009.12.047. PubMed PMID: 20085708.

Chandran V, Fronzes R, Duquerroy S, Cronin N, Navaza J, Waksman G.
Structure of the outer membrane complex of a type IV secretion system.
Nature. 2009 Dec 24;462(7276):1011-5. doi: 10.1038/nature08588. Epub 2009 Nov 29. PubMed PMID: 19946264; PubMed Central PMCID: PMC2797999.

Fronzes R, Christie PJ, Waksman G.
The structural biology of type IV secretion systems.
Nat Rev Microbiol. 2009 Oct;7(10):703-14. doi: 10.1038/nrmicro2218. Review. PubMed PMID: 19756009; PubMed Central PMCID: PMC3869563.

Meng G, Fronzes R, Chandran V, Remaut H, Waksman G.
Protein oligomerization in the bacterial outer membrane (Review).
Mol Membr Biol. 2009 Apr;26(3):136-45. doi: 10.1080/09687680802712422. Epub 2009 Feb 14. Review. PubMed PMID: 19225986.

Fronzes R, Schäfer E, Wang L, Saibil HR, Orlova EV, Waksman G.
Structure of a type IV secretion system core complex.
Science. 2009 Jan 9;323(5911):266-8. doi: 10.1126/science.1166101. PubMed PMID: 19131631.

Fronzes R, Remaut H, Waksman G.
Architectures and biogenesis of non-flagellar protein appendages in Gram-negative bacteria.
EMBO J. 2008 Sep 3;27(17):2271-80. doi: 10.1038/emboj.2008.155. Review. PubMed PMID: 18668121; PubMed Central PMCID: PMC2500206.

Backert S, Fronzes R, Waksman G.
VirB2 and VirB5 proteins: specialized adhesins in bacterial type-IV secretion systems?
Trends Microbiol. 2008 Sep;16(9):409-13. doi: 10.1016/j.tim.2008.07.001. Epub 2008 Aug 14. PubMed PMID: 18706815.

Goyon V, Fronzes R, Salin B, di-Rago JP, Velours J, Brèthes D.
Yeast cells depleted in Atp14p fail to assemble Atp6p within the ATP synthase and exhibit altered mitochondrial cristae morphology.
J Biol Chem. 2008 Apr 11;283(15):9749-58. doi: 10.1074/jbc.M800204200. Epub 2008 Feb 5. PubMed PMID: 18252710; PubMed Central PMCID: PMC2442300.

Bayliss R, Harris R, Coutte L, Monier A, Fronzes R, Christie PJ, Driscoll PC, Waksman G.
NMR structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system.
Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1673-8. Epub 2007 Jan 23. PubMed PMID: 17244707; PubMed Central PMCID: PMC1785264.

Fronzes R, Weimann T, Vaillier J, Velours J, Brèthes D.
The peripheral stalk participates in the yeast ATP synthase dimerization independently of e and g subunits.
Biochemistry. 2006 May 30;45(21):6715-23. PubMed PMID: 16716082.

Fronzes R, Chaignepain S, Bathany K, Giraud MF, Arselin G, Schmitter JM, Dautant A, Velours J, Brèthes D.
Topological and functional study of subunit h of the F1Fo ATP synthase complex in yeast Saccharomyces cerevisiae.
Biochemistry. 2003 Oct 21;42(41):12038-49. PubMed PMID: 14556635.